Introduction. Crush syndrome is the second common cause of mortality of post direct traumatic of debris affected by EARTHQUAKE. Acute renal failure secondary to crush syndrome is an incomparable acute renal failure that have surgical and internal complications and needs renal replacement therapy.Methods. This recent comprehensive study is a retrospective and prospective study. After admission of every patient, all the information were accomplished in the check lists that included demographic identifications, routine and special tests, complications, duration of being buried under the debris, initial fluid resuscitation, crush syndrome, ARF, and need to dialysis. These patients, who had ARF and crush syndrome, were separated from others with physical exam and lab data. The entire patients were carefully evaluated and treated at the time of admission to see if they had AFR, need to dialysis, response to treatment, cmplications and mortality. Some patients were being followed for 3 months. After collection of data, the data were analyzed with software of SPSS, T-student, X2 and logistic regression tests.Results. In this study, 818 stricken were evaluated. Mortality was 1.4% totally. 58 patients of entire stricken (7/09%) had crush syndrome, in these patients with crush syndrome, 36 patients (62.06%) had ARF that 16 patients (44.04%) , needed dialysis. 8 patients (22.22%) with ARF were died. Correlation between sex and crush syndrome was significant. (62.1% were women and 37.9% were men, P=0.0l) Likewise, correlation between sex and need to dialysis was significant. Mean hospitalization in both groups with ARF and without had significant difference. Average elapsed hours from pulling out of the debris to first fluid resuscitation had significant difference in both groups that had dialysis and not. (11.72 and 8.41 and p=0.002). Oliguric patients needed to dialysis more than non oliguric. (nearly 4 much times) and mortality of them was more (3 much times).Discussion. Because of intent and serious complications and high mortality of crush syndrome, immediate diagnosis and treatment of patients, will improve the results. In our study rate of overall mortality was lower beside to prior studies, likewise, need to dialysis was less.